Find a Local Restaurant in Hilton Head Island, SC

Eat New American cuisine in a casual atmosphere

Thank you for visiting the Main Street Cafe & Pub website. Our restaurant in Hilton Head Island, SC serves many different New American dishes, from homemade soups and salads to sandwiches and burgers. You'll feel like part of the family with our friendly staff and relaxed, casual atmosphere. Stop by for a great meal on our comfortable outdoor patio or call us for takeout and enjoy a homemade meal in the comfort of your own home.

Place an order by calling us at 843-689-3999. You can also use the form on this page to contact us.

  • Main Street Cafe & Pub

    1411 Main Street
    Hilton Head Island, SC 29926


    Call Us
    Phone: (843) 689-3999

    Mon: 11:30AM-8:00PM
    Tue: 11:30AM-8:00PM
    Wed: 11:30AM-8:00PM
    Thu: 11:30AM-8:00PM
    Fri: 11:30AM-8:00PM
    Sat: Closed
    Sun: Closed

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